• Li YY, Wan YJ, Wei J, Xu SQ, Zeng HC, Zhang L. (2010) MicroRNA expression changes during zebrafish development induced by perfluorooctane sulfonate. J Appl Toxicol 31(3), 210-22.

Perfluorooctane sulfonate (PFOS), a kind of widely distributed environmentally organic compound, has been found to cause developmental toxicity. Although microRNAs (miRNAs) play an important role in many metabolic tasks, whether and how they are involved in the process of PFOS-induced toxicity is largely unknown. To address this problem, PFOS-induced changes in miRNAs and target gene expression in zebrafish embryos, and the potential mechanism of PFOS-induced toxic action were studied in this research. Zebrafish embryos were exposed to 1?


miR-196 is an essential early-stage regulator of tail regeneration, upstream of key spinal cord patterning events piRNA, the new non-coding RNA, is aberrantly expressed in human cancer cells