Peptide arrays are an exciting and rapidly growing technology with a broad range of applications in the basic and applied life sciences. Peptide arrays have been under development for approximately twenty-five years, and commercial versions have been available for the past decade. The arrays...
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The scientists and engineers at LC Sciences have developed platform technologies that encompass a new class of microfluidic µParaflo® reaction devices, an advanced digital light synthesizer apparatus, and picoliter scale biochemical processes.  The functionalized µParaflo® chips are particularly suited for applications where small sample consumption, contamination-free, and performance-reproducibility are primary concerns. This technology enables the […]
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PepArray Pro is available at: http://www.pepcyber.org/PepArray/ PepArray pro is a proteomics tool to provide PepArray Layout file that contains information about peptides, peptide IDs, and the array-location of the peptides to be synthesized on chip. The Layout file is required by the synthesis of an addressable peptide microarray. Peptide microarrays (PepArrays) provide powerful proteomics technology […]
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Spermatogenesis is a complex, multistep process that maintains male fertility and is sustained by rare germline stem cells. Spermatogenic progression begins with spermatogonia, populations of which express distinct markers. The identity of the spermatogonial stem cell population in the undisturbed testis is controversial due to a lack of reliable and specific markers. In a recent […]
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Macrophage migration inhibitory factor (MIF) is a pro-inflammatory cytokine that mediates the host response to infection and stress by activating innate and adaptive immune pathways. MIF is released both from immune and neuroendocrine cells and it acts to counterregulate the immunosuppressive effect of glucocorticoids. Recently, MIF has been associated with a number of autoimmune diseases […]
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We have now provided some examples of data reports resulting from our various peptide microarray services.  You can find the sample data sets at the following links: Epitope Mapping – http://www.lcsciences.com/documents/sample_data/epitope_sample_data.zip Kinase Substrate Profiling – http://www.lcsciences.com/documents/sample_data/kinase_sample_data.zip  
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Quickly extract sequence-based biological information from improved peptide array binding results and provide more precise and accurate information about the biological systems investigated. A main objective of analyzing peptide array-based binding experiments is to uncover the relationship between a peptide sequence and the binding outcome. Limited by the peptide array technologies available for applications, few […]
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Identification of antibody or other protein:protein binding epitopes and their characterization at the amino acid level Understanding antibody specificity at the molecular level provides the key to optimizing their use as research or diagnostic tools – it forms the basis of their application as therapeutic agents. Arrays of protein sequence-derived short peptides have emerged as […]
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Visit LC Sciences at AACR 2013 Booth #2260 You’re invited to come by and discover the breath of services offered by LC Sciences to assist you in making breakthrough cancer research discoveries! Meet our Team: Chris Hebel, Vice President of Business Development Dr. Qi Zhu, Senior Scientist Jason Mulcahey, Account Manager, Genomics Division Drop by […]
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Epitope Mapping on a Flexible Microfluidic Chip Platform Understanding antibody specificity at the molecular level provides the key to optimizing their use as research or diagnostic tools – it forms the basis of their application as therapeutic agents. Arrays of protein sequence-derived short peptides have emerged as a powerful tool to identify and characterize such […]
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