The recognition and translation of mammalian mitochondrial mRNAs are poorly understood. Therefore, to gain further insights into these processes in vivo, researchers from the University of Western Australia characterized mice with a missense mutation that caused loss of the translational activator of cytochrome oxidase subunit I (TACO1)...
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PepArray Pro is available at: http://www.pepcyber.org/PepArray/ PepArray pro is a proteomics tool to provide PepArray Layout file that contains information about peptides, peptide IDs, and the array-location of the peptides to be synthesized on chip. The Layout file is required by the synthesis of an addressable peptide microarray. Peptide microarrays (PepArrays) provide powerful proteomics technology […]
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Researchers at the Medical Research Council Laboratory of Molecular Biology, Cambridge, UK set out to resolve the superstructure of the centromeric complex of TubZRC plasmid partitioning systems. The Bacterial plasmid partitioning system TubZRC consists of two proteins, tubulin-like TubZ and TubR, and a DNA centromere, tubC which functions by segregating plasmids into each daughter cell. […]
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Williams BA, Diehnelt CW, Belcher P, Greving M, Woodbury NW, Johnston SA, Chaput JC. (2009) Creating protein affinity reagents by combining peptide ligands on synthetic DNA scaffolds. J Am Chem Soc 131(47), 17233-41. [abstract] A full understanding of the proteome will require ligands to all of the proteins encoded by genomes. While antibodies represent the […]
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Identification and Sequence Composition Characterization of Chondroitin Sulfate-Binding Peptides through Peptide Array Screening Researchers at Arizona State University made use of LC Sciences Custom Peptide Microarray Service and demonstrated an effective methodology to identify and characterize Chrondroitin sulfate (CS) binding peptides for sequence composition.  Butterfield K, Caplan M, Panitch A. (2010) Identification and Sequence Composition […]
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A platform technology that encompass a new class of microfluidic µParaflo® reaction devices, an advanced digital light synthesizer apparatus, and picoliter scale biochemical processes.  The functionalized µParaflo® chips are particularly suited for applications where small sample consumption, contamination-free, and performance-reproducibility are primary concerns. This technology enables the massively parallel synthesis of high quality DNA and […]
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