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  • Publications
        • Featured Customer Publication

          Construction of a scFv Library with Synthetic, Non-combinatorial CDR Diversity
          Construction of a scFv Library with Synthetic, Non-combinatorial CDR Diversity
          Many large synthetic antibody libraries have been designed, constructed, and successfully generated high-quality antibodies suitable for various demanding applications...
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        • The Latest Customer Publications

          Long noncoding RNA GAS5 inhibits progression of colorectal cancer by interacting with and triggering YAP phosphorylation and degradation and is negatively regulated by the m6A reader YTHDF3
          YTHDF1 links hypoxia adaptation and non-small cell lung cancer progression
          MicroRNA528, a hub regulator modulating ROS homeostasis via targeting of a diverse set of genes encoding copper-containing proteins in monocots
          The effect of cadmium on the microRNAome, degradome and transcriptome of rice seedlings
          Revealing of MicroRNA Involved Regulatory Gene Networks on Terpenoid Biosynthesis in Camellia sinensis in Different Growing Time Points
          Investigation on the role of gene hp0788 in Helicobacter pylori in infecting gastric epithelial cells
          Integrated transcriptome, small RNA, and degradome analysis reveals the complex network regulating starch biosynthesis in maize
          Transcriptome sequencing reveals phagocytosis as the main immune response in the pathogen-challenged sea urchin Strongylocentrotus intermedius
          Aberrant ERG expression associates with downregulation of miR-4638-5p and selected genomic alterations in a subset of diffuse large B-cell lymphoma
          Analysis of the microRNA expression profiles in feline kidney cell line infected with feline panleukopenia virus
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        • Featured Poster

           Identification of Novel Protein Interaction Networks in Tyrosine Kinase Signaling Pathways
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          Targeted NGS for investigating the mitochondrial genome and heteroplasmy

           Targeted NGS for investigating the mitochondrial genome and heteroplasmy

          Disrupted mitochondrial functions and genetic variants of mitochondrial DNA (mtDNA) have been observed in different human neoplasms. Next-generation sequencing (NGS) can be used to detect even low heteroplasmy-level mtDNA variants.…

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        • The Latest News

          RNA sequencing reveals gene network regulated terpenoid biosynthesis in tea plant (Camellia sinensis)
          Join LC Sciences at ASHG 2019 – Oct 15-19 – Houston, TX
          Researchers use CRISPR screening to define a diverse landscape of DNA damage response gene mutations
          Extracellular vesicle contents in synovial fluid may serve as a diagnostic for arthritic disease and indicator for therapeutic efficacy of senolytic treatment
          Researchers demonstrate the feasibility of a microRNA-based therapy for promoting wound closure
          Researchers unravel a causal link between cocaine use, gut-barrier dysfunction and dysbiosis
          RNA Sequencing reveals Wipi1 a potential target for right ventricular-directed heart failure therapy
          Targeted NGS is a reliable method for investigating the mitochondrial genome and heteroplasmy
          Extracellular vesicle contents found in synovial fluid may serve as a diagnostic for arthritic disease
          Extracellular MiRNA Cargo Play Important Role in Manipulation of Host Phenotype During Parasitic Infection
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          LC Sciences is a global biotechnology company providing products and services to genomics and proteomics researchers across an array of markets for nucleic acid/protein analysis, biomarker-discovery and drug development.
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          VariantPro™ Targeted Sequencing Technology

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Support Documents

  1. Home
  2. Applications
  3. Transcriptomics
  4. microRNA Discovery & Profiling
  5. microRNA Sequencing Service
  6. Support Documents

Application Notes

MicroRNA Sample Preparation from Biofluid Samples

MicroRNA Sample Preparation from Biofluid Samples

The study of basic microRNA (miRNA) function has been performed mainly through collection of tissues by invasive methods. However, in a clinical setting…

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MicroRNA Sample Preparation from Serum/Plasma Samples

MicroRNA Sample Preparation from Serum/Plasma Samples

The study of basic microRNA (miRNA) function has been performed mainly through collection of tissues by invasive methods. However, in a clinical setting…

read more

Small Non-coding RNA Discovery

Small Non-coding RNA Discovery

Non-coding (ncRNAs) are a large class of RNAs which do not encode proteins but possess regulatory functions at the level of translation in cells of various…

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MicroRNA expression analysis of blood samples can further our understanding of diseases of the blood

MicroRNA expression analysis of blood samples can further our understanding of diseases of the blood

The regulatory effects microRNA of are widespread and microRNAs have recently been implicated in various diseases of the blood, stem cells, brain, and…

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microRNA profiling of FFPE tissue samples

microRNA profiling of FFPE tissue samples

Archiving histological tissue samples by formalin-fixing and embedding in paraffin blocks has been a routine practice for medical and research…

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MicroRNA Profiling Increases Understanding of Molecular Circuitry

MicroRNA Profiling Increases Understanding of Molecular Circuitry

The mechanism of regulation by microRNA (miRNA) is complex in that miRNAs are frequently transcribed together as primary transcripts that are then…

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MicroRNAs play a critical role in immune system by regulating/fine tuning inflammatory response

MicroRNAs play a critical role in immune system by regulating/fine tuning inflammatory response

MicroRNAs (miRNAs) have proven to be an extremely important part of the gene expression regulation mechanism. As the first miRNA microarray service…

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Integrating microRNA and mRNA expression profiles for identification of regulatory networks

Integrating microRNA and mRNA expression profiles for identification of regulatory networks

The discovery of microRNA as an additional regulatory mechanism has been a revolution to the field of Developmental Biology. While early research has…

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MicroRNAs as Potential Biomarkers in Cancer and Heart Disease

MicroRNAs as Potential Biomarkers in Cancer and Heart Disease

Heart disease and cancer represent the number one and number two killer diseases in developed countries. Identifying biomarkers to detect these and other…

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The many complex roles of microRNA in breast cancer

The many complex roles of microRNA in breast cancer

There have been several studies involving microRNAs and breast cancer to date. These studies collectively demonstrate the wide range of functions…

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Technical Bulletins

Technical Bulletin – microRNA Sequencing Service - In Depth Data Analysis Guide

Technical Bulletin – microRNA Sequencing Service - In Depth Data Analysis Guide

A 15 minute video that walks you step-by-step through the files you receive from our microRNA sequencing service - LC Sciences' miRNA sequencing service…

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RNA Sequencing Service Overview

RNA Sequencing Service Overview

Transcriptomics, or genome-wide expression profiling, aims to catalogue the complete set of RNA transcripts produced by the genome…

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Biological Replicate Considerations - Differential Expression Analysis

Biological Replicate Considerations - Differential Expression Analysis

Although next-generation sequencing and microarray service is becoming more and more affordable every year, these projects still represent a significant...

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Total RNA Sample Preparation for RNA Analysis Studies

Total RNA Sample Preparation for RNA Analysis Studies

The amount of total RNA required for library preparation depends on the profiling service requested. Please see our RNA sequencing service comparison chart…

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International Shipping Instructions - Total RNA Samples

International Shipping Instructions - Total RNA Samples

LC Sciences provides the following information to facilitate the international shipment of total RNA samples. We serve many customers overseas and …

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Customer Quality Control Checks of RNA Sample

Customer Quality Control Checks of RNA Sample

Quality of total RNA samples is upmost important to the success of miRNA array assays. Three quality controls are performed including quantity, purity…

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RNA Sequencing Services Comparison

RNA Sequencing Services Comparison

New RNA sequencing methods enable discovery and profiling of RNAs in any organism without prior genome annotation. Rapid advancement of new technologies has led to the development of several methods...

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Total RNA Preparation for microRNA Analysis Studies

Total RNA Preparation for microRNA Analysis Studies

For each sample, we ask that you try to send in at least 1-3 µg of total RNA. Please transfer your sample…

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Product Literature

Product Brochure – microRNA Discovery & Profiling Services

Product Brochure – microRNA Discovery & Profiling Services

LC Sciences provides a comprehensive sequencing service utilizing Illumina,s high-throughput sequencing technology which enables comprehensive, highly sensitive…

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Product Brochure - Seq-Array™ for microRNA Discovery & Profiling

Product Brochure - Seq-Array™ for microRNA Discovery & Profiling

Seq-Array offers a customized solution to high-throughput genome-wide miRNA discovery and profiling, especially in species with limited or no miRNA sequence information available. This unique combination of the latest deep sequencing technology, advanced bioinformatics, and our innovative μParaflo® custom microarray platform leverages all these technologies to form a comprehensive service package tailored to your specific research needs.

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Product Brochure - RNA Sequencing Services

Product Brochure - RNA Sequencing Services

Next-gen sequencing is a new method and powerful tool used to identify and quantitatively decode the entire population of small RNAs in your total RNA sample…

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Ordering Information

Technical Information

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West Bellfort Street
Suite 270
Houston, TX
77054 USA

Local (713) 664-7087
Toll Free: 1-888-528-8818
Fax: (713) 664-8181
www.lcsciences.com

About Us

LC Sciences is a global biotechnology company providing products and services to genomics and proteomics researchers across an array of markets for nucleic acid/protein analysis, biomarker-discovery and drug development.

The Latest News

RNA sequencing reveals gene network regulated terpenoid biosynthesis in tea plant (Camellia sinensis)
Join LC Sciences at ASHG 2019 – Oct 15-19 – Houston, TX
Researchers use CRISPR screening to define a diverse landscape of DNA damage response gene mutations
Extracellular vesicle contents in synovial fluid may serve as a diagnostic for arthritic disease and indicator for therapeutic efficacy of senolytic treatment
Researchers demonstrate the feasibility of a microRNA-based therapy for promoting wound closure
Researchers unravel a causal link between cocaine use, gut-barrier dysfunction and dysbiosis

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