Targeted NGS for investigating the mitochondrial genome and heteroplasmy
Disrupted mitochondrial functions and genetic variants of mitochondrial DNA (mtDNA) have been observed in different human neoplasms. Next-generation sequencing (NGS) can be used to detect even low heteroplasmy-level mtDNA variants.…
LC Sciences is a global biotechnology company providing products and services to genomics and proteomics researchers across an array of markets for nucleic acid/protein analysis, biomarker-discovery and drug development.
VariantPro™ is an innovative multiplex PCR-based targeted sequencing method that accomplishes target selection, library preparation and molecular tagging in a simple one-step workflow. The method incorporates novel Relay-PCR™ and Omega Primer™ technologies to produce amplicons of high uniformity & specificity.
Designed for 100% amplicon coverage (16,569 bp) of the mitochondrial genome, the Mitochondrion Panel offers cost-effective, minimal hands-on, ultra-high resolution…