LC Sciences has discontinued our Gene Expression Microarray Service. We Sciences now offers a comprehensive Gene Expression Sequencing Service featuring the lastest-in RNA-Seq technology. Sequencing holds many advantages over traditional microarray profiling and can be a less expensive option then microarrays.
The incredible power of RNA-Seq was initially applied primarily for complex whole transcriptome applications such as discovery of rare genes, splice junctions and gene fusions or for study of novel and less well-characterized organisms. However, as the technology is improving and costs are decreasing, RNA sequencing is now suitable to be used for simple RNA profiling (sample comparison) as well.
RNA-Seq in fact holds several advantages over microarrays for gene expression analysis applications:
- Expression profiling is truly genome-wide – there is no need for probes based on prior sequence information.
- Powerful RNA-Seq technology reads every base of every transcript – this is not TAG profiling.
- Achieve digital transcript expression analysis – accurate quantitation of expression levels over 5 orders of magnitude of transcript abundance.
