miRNA plays an integral role in many neurological pathologies

miRNAs are implicated in the pathogenesis of numerous neurodegenerative diseases, including Parkinson’s disease. They regulate important targets that can influence the function of neurons and thus can be potential therapeutic targets for the neurodegenerative diseases.

miRNAs modulate important repressors of the inflammatory response of the brain indicating the potential for anti-miRNAs as an effective therapeutic strategy against pathogenic inflammatory signaling.

Researchers have shown that the fetal transcriptome, through miRNA regulation, responds to prenatal stress in association with epigenetic signatures thus demonstrating a mechanistic association between environmental and genetic risk factors in psychiatric and neurological disease.

Read more about how LC Sciences is helping clinicians and researchers with:

LC Sciences offers a range of services applicable to clinical neuroscience research.
Contact us to find out more.

RNA Sequencing Services

microRNA Profiling Services

microRNAs are small noncoding RNA molecules that function broadly as negative regulators of gene expression to control a wide range of cellular processes. A genome-wide microRNA (miRNA) expression profiling service…