Mutation of the human genome ranges from single base-pair changes to whole-chromosome aneuploidy. Mutations are associated with a wide range of clinical problems, including cancer.
SNPs
In the past, differential profiling and functional studies have been performed mainly using tissues samples collected by invasive methods. However, in a clinical setting, more convenient and non-invasive methods are required, such as collection of peripheral blood or other bodily fluids…
Chromosome Abnormalities
A chromosome abnormality, or mutation is a missing, extra, or irregular portion of chromosomal DNA. Mutation of the human genome ranges from single base-pair changes to whole-chromosome aneuploidy. The DNA sequence of a chromosome can be altered in a number of ways including: substitutions, insertion and deletions…
Gene Fusions
Genomic translocations frequently lead to the generation of gene fusions with oncogenic properties. RNA sequencing has allowed gene expression profiling and detection of previously unknown, alternatively spliced and gene fusion transcripts with potential oncogenic roles….
Cancer Research Services
LC Sciences offers a range of services applicable to clinical cancer research . Contact us to find out more.

The VariantPro system is an innovative multiplex PCR based targeted sequencing method that accomplishes target selection, library preparation and molecular tagging in a simple one-step workflow. [ Exome sequencing is an efficient strategy to selectively sequence the coding regions of the genome as a less expensive but still effective alternative to whole genome sequencing. [
The additional knowledge gained by studying the response to antigens at the epitope level will help us further understand anti-tumor immunity and may also help us to monitor cancer progress and cancer vaccine efficacy in the future. [ Systems Biology has emerged as an effective approach to studying complex interactions within biological systems. By studying entire networks or pathways, we can better understand the underlying structure of cell signaling networks. [
microRNAs are small noncoding RNA molecules that function broadly as negative regulators of gene expression to control a wide range of cellular processes. [ Our comprehensive sequencing services make use of the latest in next-gen sequencing technologies. Illumina’s industry-leading RNA sequencing methods enable discovery [