Fluorescence in situ hybridization (FISH) utilizes fluorescent probes to bind portions of DNA that have a high degree of sequence complementarity....
Post-transcriptional gene regulation controls the amount of protein produced from an individual mRNA by altering rates of decay and translation. Although
The use of synthetic oligonucleotides for cloning complex libraries of constructs with predefined nucleic acid sequences is now a common practice
Construction of Mutagenesis Libraries for Antibody Affinity Maturation Using Microchip-synthesized Oligonucleotides
In-vitro display screening of artificial antibody libraries has proven to be a method for discovering valuable antibodies for clinical application
In recent years, antibody libraries have proven effective tools for drug discovery and development. Because many difficult therapeutic challenges cannot be addressed
Modern synthetic biology involves not only the construction of existing genes to elicit their functions, but also designed mutation and sequence shuffling...
OligoMix is a versatile, innovative, custom product for genomics discoveries. We synthesize thousands of oligonucleotide sequences in massive parallel
Color-coded expression chart visualizing positional and regional trends for siCD46 knockdown efficiency and tolerance towards double-mutations in
No flexibility in choosing codons for protein expression optimization. The NNN library has six fold difference in amino acid representation; the amount
Improved Confidence in Microarray Results – Probe Validation, Manufacturing QC, and External Reference Standards
Construction of Protein Coding Libraries
Thousands of oligonucleotides of customer specified sequences are synthesized at once on a photoprogrammable microfluidic chip and released into solution
Modern synthetic biology involves not only the construction of existing genes to elicit their functions, but also designed mutation and sequence...
To meet the growing demand for synthetic genes, more robust, scalable and inexpensive gene assembly technologies must be developed. Methods for large-scale
A collaboration by researchers from Harvard Medical School, the University of Houston, and University of Michigan demonstrates in solution hybridization
Recent major advances in DNA sequencing technologies have resulted in several new next-generation platforms capable of generating massive amounts of reads
Recently, an international team has developed a rolling-circle method for amplification (RCA) that overcomes the drawbacks associated with other amplification
Massively Parallel Oligonucleotide Synthesis on a Microchip based on the µParaflo® Microfluidics Technology
The scientists and engineers at our technology partner, Atactic Technologies, have developed platform technologies
Recent major advances in DNA sequencing technologies have resulted in several new "next-generation" platforms capable of generating massive amounts of
OligoMix is a versatile, innovative, custom product for genomics discoveries. We synthesize thousands of oligonucleotide sequences in massive parallel on a microarray chip and then cleave the oligos, releasing them into solution in a single microtube