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The Latest News can be found at LC Sciences Blog

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August 19th, 2010 - The Porcine microRNAome is Revealed - Researchers from LC Sciences LLC and a collaboration of Universities have established a porcine microRNAome, a complete catalog of all microRNAs expressed in the species Sus scrofa.  MicroRNAs (miRNAs) are small regulatory RNA molecules known to control a wide array of cellular functions such as growth and development and whose dysregulation has been associated with disease. The findings of this study blaze a trail for advancement in pig biology as well the use of pigs as model organism for human biological and biomedical studies. (read more...)

June 24th, 2010 - Transcriptome Sequence Service is now available - LC Sciences now provides a one-stop solution (i.e. from sample to data) for transcriptome sequencing using the latest in RNA-Seq technology.  RNA-Seq is a new method and a powerful tool to identify and quantitatively decode the entire population of RNAs in your sample.  The transcriptome profiling and analysis services by LC Sciences are comprehensive and provide the most complete picture of RNA content in your samples.  We can help you set up and conduct a high-quality, well-controlled RNA-Seq experiment based on the latest deep-sequencing technologies. (read more...)

April 26th, 2010 - miRBase 15.0 Content Now Available - The miRBase sequence database was just updated to version 15.0. This content is immediately available on all our standard and custom miRNA microarrays. Version 15.0 represents a 48% increase in the number of miRNA sequences over version 14.0. (read more...)

March 19th, 2010 - Seq-Array^SM  service is now available. Seq-Array^SM offers a customized solution to high-throughput genome-wide microRNA discovery and profiling, especially in species with limited or no microRNA sequence information available. This unique combination of the latest deep sequencing technology, advanced bioinformatics, and our innovative µParaflo® custom microarray platform leverages all these technologies to form a comprehensive service package tailored to your specific research needs. (read more...)

December 11th, 2009 - LC Sciences' microRNA Microarray customers publish in Science Magazine - This groundbreaking work identified miR-206 as a modifier of Amyotrophic lateral sclerosis (ALS)  pathogenesis and provides a new perspective on the mechanisms underlying this neurodegenerative disease. (read more...)

October 8th, 2009 - The plant miRNA database (PMRD) integrates available plant miRNA data deposited in public databases, gleaned from the recent literature, and data generated by the database organizers. This database contains sequence information, secondary structure, target genes, expression profiles and a genome browser. In total, there are 8433 miRNAs collected from 121 plant species in PMRD, including model plants and major crops such as Arabidopsis, rice, wheat, soybean, maize, sorghum, barley, etc in this first edition of the database. (read more...)

September 15th, 2009 - miRBase updated to version 14.0. 1580 new mature miR and miR* sequences comprise a significant update to the sequence database which has now topped 10,000 entries.  This latest release features new sequences for all the important model species as well as many important agricultural plants. (read more...)

September 11, 2009 - LC Sciences Blog launched. Check the blog for company news, product updates, press releases, company events, and new customer publications. (read more...)

March 9, 2009 - With the addition of 1004 new mature miRNA sequences, the Sanger microRNA Sequence Database (miRBase) announced a significant update to the miRBase sequence database.  This latest release is miRBase version 13.0 and features a total of 9169 mature miRNA sequences. (read more...)

February, 2009 - Targeted Sequencing - Sample Enrichment Service Available - Take advantage of high-throughput sequencing technologies with target-specific selection of defined sequences of your interest.  Genomic DNA, PCR product, or RNA accepted.

January, 2009 - microRNA/ small RNA Sequencing Services Launched - Now a one-stop solution for all your small RNA discovery, detection and expression profiling needs.

Sept 1, 2008 - The Sanger Institute announces the largest single update in the history of miRBase with the of 2062 new mature miRNA sequences.  In addition to sequence updates and additions to species included in previous miRBase versions, mature miRNA sequences from many new species are included for the first time. (read more...)

April, 2008 - The Sanger miRBase sequence database was updated to release version 11.0.  The number of verified microRNAs has been increased from 5395 to 6396 hairpin precursor miRNAs expressing 6211 mature miRNA products.  This latest microRNA sequence content is currently available on all our standard and custom microRNA microarrays.  (read more...)

February, 2008 - microRNA qRT-PCR Service Launched - LC Sciences now provides a one-stop solution for all your microRNA (miRNA) expression profiling needs.  We can provide you with both microarray and qRT-PCR profiling services for the most complete picture of microRNA expression in your samples.

January, 2008 - LC Sciences now offers Gene Expression Analysis Service by Affymetrix GeneChip^® through our partnership with SeqWright DNA Technology Services, an Affymetrix-authorized service provider. This service is GLP-compliant for handling patient samples. We offer 5 day turnaround on most projects.

January, 2008 - PepCyber Now Online - A searchable database of human protein–protein interactions mediated by phosphoprotein-binding domains.

December, 2007 - The Sanger miRBase sequence database was updated to release version 10.1.  This marks the fourth update this year.  The number of verified microRNAs has been increased from 5071 to 5395 hairpin precursor miRNAs expressing 5234 mature miRNA products.  This latest microRNA sequence content is currently available on all our standard and custom microRNA microarrays.  (read more...)

Press Releases

LC Sciences today announced the launch of its new Seq-Array^SM services designed to take full advantage of both the latest deep sequencing capabilities and the proven genomics tool – microarray. This combination of technologies advances microRNA research to the next level of depth and understanding that was not possible before with either of the technologies alone. LC Sciences has been a leading provider of microRNA discovery and profiling services since 2005.

Taking full advantage of its flexible µParaflo® Biochip Technology, Houston based LC Sciences today announced immediate availability of probe content from the newly created Plant MicroRNA Database (PMRD) for their microRNA (miRNA) microarray customers. This announcement comes immediately following a publication in Nucleic Acids Research introducing the public database¹. The PMRD integrates available plant miRNA data deposited in other public databases, gleaned from the recent literature, and data generated by the database organizers. It is freely available at http://bioinformatics.cau.edu.cn/PMRD.

LC Sciences announced today the publication of the 100th peer-reviewed study by one of its customers using the company’s microarray service for analyzing microRNA (miRNA) expression profiles and for discovery of novel small RNAs. These studies, by leading researchers in the field, contribute to a fast growing body of knowledge defining this recently discovered class of regulatory RNAs.

February 26th, 2009 - LC Sciences’ Versatile Microfluidics Chip Technology Extended to Target Selection Applications

LC Sciences has announced the availability of a custom target enrichment service for next-generation sequencing applications.  LC Sciences now provides a service for Target-Specific Selection of a defined genomic region (such as Mbp region at a specific location, suspected cancer regions, SNP regions, regions for genomic comparisons) or RNA sequences (such as sets of transcriptome sequences known from previous screening experiments, mRNAs, and miRNAs).  This new service enables researchers to take full advantage of new “next-generation” high throughput sequencing technologies. (read more...)

September 17th, 2008 - Novel Small RNAs Discovered, Contribute to Significant miRBase Update

Non-coding (ncRNAs) are a large class of RNAs which do not encode proteins but possess regulatory functions at the level of translation in cells of various species.  There are an increasing amount of data suggesting that there are likely many more ncRNAs that exist, yet to be discovered.  Custom small RNA discovery microarrays have been shown to be an effective approach for uncovering novel ncRNAs experimentall and/or to validate predicted candidate ncRNAs. (read more...)

May 6th, 2008 - LC Sciences and DNAVision form Strategic Marketing Alliance

LC Sciences announced today that it has entered into a strategic marketing alliance with DNAVision to increase accessibility to its custom microRNA profiling service and enhance both its customer and technical service to researchers in Europe.  LC Sciences’ microRNA profiling service is powered by µParaflo® microfluidic technology and makes use of flexible custom microarrays for expression profiling as well as discovery of novel small RNAs and validation of predicted microRNAs.  DNAVision, specialized in molecular biology, provides a wide range of genetic services and products to the pharmaceutical, food, and biotechnology industries. (read more...)

LC Sciences announced today the publication of the 30th peer-reviewed study by one of its customers using the company’s microarray service for analyzing microRNA expression profiles and for discovery of novel small RNAs. These studies, by leading researchers in the field, contribute to a fast growing body of knowledge defining this recently discovered class of regulatory RNAs. (read more...)

August 9, 2007 - LC Sciences First miRNA Microarray Service Provider to Offer Sanger’s miRBase 10.0 Probe Content

Houston, TX – August 9, 2007 – Taking advantage of its flexible µParaflo^®Chip Technology, Houston based LC Sciences today announced immediate availability of probe content miRBase 10.0 for their microRNA (miRNA) microarray customers. (read more...)

Houston, TX – May 9, 2006 – LC Sciences announced today that the probe content of its line of standard and custom microRNA microarrays used in their comprehensive expression profiling service would keep pace with the latest version (Release 8.1) of the Sanger miRBase sequence database. (read more...)

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