Our comprehensive microarray services include the use of custom synthesized microarrays based on the µParaflo® on-chip synthesis technology which enables the total customization of content on each individual microarray to suit your needs.
The aptamer microarrays are applied for protein bindings, drug candidate screening, and biosensor engineering.
Our comprehensive services includes sequence retrieval from public databases and literature, and/or assistance with your sequence designs, nucleic acid hybridization assays using samples provided by you, single or dual color detection of the hybridization using a suitable method, image data processing, and signal data processing.
LC Sciences provides a genome-wide microRNA (miRNA) expression profiling service using µParaflo® technology and proprietary probe design, which enable highly sensitive and specific direct detection of miRNAs. We have standard arrays for mature miRNA of all species available in the latest version of the miRBase database (Release 19).
LC Sciences provides a small non-coding RNA microarray service for discovery of novel small regulatory/functional RNA embedded within non-coding RNAs (ncRNAs) or genomic RNAs.
LC Sciences provides access to Gene Expression Analysis Service through our partnership with SeqWright DNA Technology Services. SeqWright is an Affymetrix® Authorized Service Provider with over 30 years of combined experience involving microarray technologies used in both industry and diagnostic environments.
LC Sciences provides a comprehensive kinase analysis service utilizing high density protein kinase substrate (PKS) peptide microarrays based on PepArray™ technology for proteomic scale kinase profiling, quantitative measurement of kinase kinetic activities, and drug discovery research.
Through the use of overlapping peptides as epitopes on a custom synthesized addressable peptide microarray (PepArray™), we can systematically screen thousands of sequences in a single experiment. This combination of high-throughput capacity with quantitative measurement enables us to quickly and efficiently identify high affinity and high specificity target binding compounds.
LC Sciences now offers customizable parallel synthesis and microfluidic technologies to create a microarray of thousands of peptides for binding to your protein or antibody sample and a comprehensive protein and/or antibody analysis service utilizing these high density peptide microarrays for high throughput detection, concentration titration, and screening applications.
The PepArray™ technology involves in situ (on chip) high density peptide synthesis and multiplex protein assays carried out in a microfluidic picoliter scale microarray. These are custom synthesized peptide microarrays (see PepArray™ technology) containing 4K-30K features. Each feature is actually a miniature (37-270 pl) reaction chamber.