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Specialty Proteomics Microarrays

Specialty Proteomics Microarrays

 

 

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Application Notes

Our proteomics products and services include the use of custom synthesized microarrays based on the µParaflo® on-chip synthesis technology which enables the total customization of content on each individual microarray to suit your needs. Our comprehensive services includes sequence retrieval from public databases and literature, and/or assistance with your sequence designs, enzymatic and binding assays using samples provided by you, single or dual color detection using a suitable method, image data processing, and signal data processing.

Applications

  • Assay SHP2 and SH2 Proteins  (See PepCyber :P~Pep Website)
  • Peptidomimetics Studies
  • Enzyme reactivity studies
  • Pathway studies
  • Protein-protein interactions
  • Phosphotyrosine binding protein (PTB) studies

µParaflo® on-chip synthesis technology provides the flexibility of synthesizing microarrays containing probes with modifications such as phosphopeptides, peptidomimetics, other amino acid analogs or various other types of modifications. These specialty proteomics products serve needs for enzyme reactivity studies, pathway studies, protein-protein interactions, phosphotyrosine binding protein (PTB) studies, and more.

These products significantly reduce the cost and increase the speed of highly multiplexing experiments.

Proprietary µParaflo® technology enables simple, high-throughput, quantitative, and flexible methods for detection.

  • In situ synthesized on an addressable high density microfluidics chip
  • Customer specified peptide or oligonucleotide sequences
  • Standard synthesis chemistry ensures high quality synthesis
  • Thousands of sequences per chip
  • Perform thousands of reactions in parallel: 1 chip = 40 x 96-well plates
  • No minimum order

Simple

  • Simple controllable process - use of chips is highly automated though it does not require expensive robotic equipment.
  • Compatible platform - microchips chips are compatible with standard microarray equipment
  • Standard synthesis chemistry - ensures high quality synthesis.

High Throughput

  • Target thousands of sequences at once - perform thousands of reactions in parallel at addressable chip locations.
  • 1 Chip = 40 X 96-well plates
  • Reduce consumption of valuable samples to the sub-nanoliter to picoliter level.
  • Scaleable to proteomic scale.

Quantitative

  • Generate information about specific peptide or oligonucleotide sequences - sequences can be defined to each single residue/base and the interpretation of the assay results are taken directly from image read out of an addressable microarray.
  • Make use of convenient, safe, sensitive fluorescence detection.
  • Ensure reliable and quantifiable results through the use of extensive negative and positive control references.

Flexible

  • Customer can choose from our standard microarray content, customer specified sequences and layout, or sequences custom designed by LC Sciences.
  • Quickly revise microarray content.
  • Incorporate modifications to expand the range of applications.

Fast

  • Receive your data in just 2-3 weeks time.

Ordering Information

 

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