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Proteomics |
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Our proteomics products and services include the use of custom synthesized peptide microarrays based on the µParaflo®on-chip synthesis technology which enables the total customization of content on each individual microarray to suit your needs. Our comprehensive services includes sequence retrieval from public databases and literature, and/or assistance with your sequence designs, binding and enzymatic assays using protein kinases, antibodies, or other proteins provided by you, single or dual color detection of the binding using a suitable method, image data processing, and signal data processing. LC Sciences offers additional µParaflo® technology derived proteomics products that serve needs for construction of biomolecular libraries containing up to millions of different biomolecules of defined sequences.
Kinase Profiling Microarray ServiceLC Sciences provides a comprehensive kinase analysis service utilizing high density protein kinase substrate(PKS) peptide microarrays synthesized on µParaflo® microfluidic chips for proteomic scale kinase profiling, quantitative measurement of kinase kinetic activities in the absence or presence of protein kinase inhibitors, and drug discovery research. This comprehensive service includes synthesis of standard or customized peptide array, performing enzymatic assay, array data acquisition, data analysis and completion of report. Two-three weeks after receiving your kinase sample(s), we send you a data summary report containing background subtraction, control and reference signal guided data processing, list of detected signals, and data averaging. We offer additional services for in-depth kinetic data analysis and curve analysis of quantitative measurements.
Protein Binding Microarray ServiceLC Sciences provides a comprehensive service for custom peptide microarray experiments utilizing high density peptide and epitope microarrays synthesized on µParaflo® microfluidic chips for quantitative assays using recombinant proteins/antibodies or serum samples. These quantitative assays are applicable for immunological studies, vaccine development, and biosensor development. This comprehensive service includes assistance with your sequence designs, binding assays using sample(s) provided by you, single or dual color detection of the binding using a suitable method, image data processing, and signal data processing. Two-four weeks after receiving your sample(s), we send you a data summary report containing background subtraction, control and reference signal guided data processing, list of detected signals, and data averaging. We offer additional services for in-depth binding data analysis and curve analysis of quantitative measurements.
Aptamer Binding Microarray ServiceLC Sciences provides unique aptamer microarray services using a novel µParaflo® technology, a list of aptamer sequences, and sequence design software to suit biosensor, binding ligand needs for basic research and screening of aptamers as drug candidates. This comprehensive service includes assistance with sequence design, synthesis of standard or custom DNA/RNA (2’-OMe) microarrays, binding assays using proteins, nucleic acids, carbohydrates, or other kinds of small molecules provided by you, single or dual color detection and quantitative measurement of the binding using a suitable method, image data processing, and signal data processing. Two-four weeks after receiving your sample(s), we send you the analyzed data, representative and original images of the array, and raw data. We offer additional services for in-depth binding data analysis and curve analysis of quantitative measurements.
Specialty Proteomics MicroarraysThe µParaflo® technology also provides the flexibility of synthesizing microarrays containing probes with modifications such as phosphopeptides, peptidomimetics, other amino acid analogs or various other types of modifications. Incorporation of modifications greatly increases the number of applications for these microarrays. Two-four weeks after receiving your sample(s), we send you the analyzed data, representative and original images of the array, and raw data. We offer additional services for in-depth binding data analysis and curve analysis of quantitative measurements.
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