Press

Sichuan Agricultural University and LC Sciences Uncover the Epigenetics of Obesity

Hangzhou, China – May 29, 2012 - In a new study published online in Nature Communications, researchers from Sichuan Agricultural University and LC Sciences report the miRNAome in porcine adipose and muscle tissues. The report provides a valuable epigenomic source for obesity prediction and prevention and furthers the development of pig as a model organism for human obesity research. (read more… )

Enabling microRNA Discoveries – 250th peer-reviewed publication made possible by µParaflo® custom microarray technology

Houston – June 9, 2011 – LC Sciences, a life sciences company leading the development of innovative microRNA (miRNA) analysis and discovery technologies, announced today the publication of over 250 peer-reviewed studies using the company’s microarray service for analyzing miRNA expression profiles. These studies, by leading researchers in the field, represent significant steps toward realizing these small regulatory RNA’s potential as biomarkers and therapeutic targets. (read more… )

LC Sciences Launches V17 MicroRNA Microarrays

Houston – May 11, 2011 - Taking advantage of its flexible µParaflo^® Chip Technology, Houston based LC Sciences today announced immediate availability of probe content from miRBase 17 for their microRNA (miRNA) microarray customers. This announcement comes just a few days after the announcement of the update to version 17 at miRBase.org (http://www.mirbase.org/blog/2011/04/mirbase-17-released/).  (read more… )

The Porcine microRNAome is Revealed

Results blaze a trail for advancement in pig biology as well the use of pigs as model organism for human biological and biomedical studies

Houston – August 19, 2010 – Researchers from LC Sciences LLC and a collaboration of Universities¹ have established a porcine microRNAome, a complete catalog of all microRNAs expressed in the species Sus scrofa².  MicroRNAs (miRNAs) are small regulatory RNA molecules known to control a wide array of cellular functions such as growth and development and whose dysregulation has been associated with disease. The findings of this study lay the groundwork for a greater understanding of the species through further mapping of tissue- and stage-specific miRNAs. (read more… )

LC Sciences Pairs Deep Sequencing with Customized Microarrays to Offer New Seq-ArraySM Service for Discovery & Profiling Applications

Houston – Mar 19, 2010 – LC Sciences today announced the launch of its new Seq-Array^SM services designed to take full advantage of both the latest deep sequencing capabilities and the proven genomics tool – microarray. This combination of technologies advances microRNA research to the next level of depth and understanding that was not possible before with either of the technologies alone. LC Sciences has been a leading provider of microRNA discovery and profiling services since 2005. (read more… )

LC Sciences First miRNA Microarray Service Provider to Offer Plant MicroRNA Database (PMRD) Probe Content

Houston, TX – October 15, 2009 – Taking full advantage of its flexible µParaflo® Biochip Technology, Houston based LC Sciences today announced immediate availability of probe content from the newly created Plant MicroRNA Database (PMRD) for their microRNA (miRNA) microarray customers. This announcement comes immediately following a publication in Nucleic Acids Research introducing the public database¹. The PMRD integrates available plant miRNA data deposited in other public databases, gleaned from the recent literature, and data generated by the database organizers. It is freely available at http://bioinformatics.cau.edu.cn/PMRD. (read more… )

Enabling microRNA Discoveries – LC Sciences tops 100th customer publication

Houston, TX – September 4, 2009 – LC Sciences announced today the publication of the 100th peer-reviewed study by one of its customers using the company’s microarray service for analyzing microRNA (miRNA) expression profiles and for discovery of novel small RNAs. These studies, by leading researchers in the field, contribute to a fast growing body of knowledge defining this recently discovered class of regulatory RNAs. (read more… )

LC Sciences’ Versatile Microfluidics Chip Technology Extended to Target Selection Applications

Houston, TX – Feb 26th, 2009 – LC Sciences has announced the availability of a custom target enrichment service for next-generation sequencing applications.  LC Sciences now provides a service for Target-Specific Selection of a defined genomic region (such as Mbp region at a specific location, suspected cancer regions, SNP regions, regions for genomic comparisons) or RNA sequences (such as sets of transcriptome sequences known from previous screening experiments, mRNAs, and miRNAs).  This new service enables researchers to take full advantage of new “next-generation” high throughput sequencing technologies. (read more… )

Novel Small RNAs Discovered, Contribute to Significant miRBase Update

Houston, TX – Sept 17th, 2008 -Non-coding (ncRNAs) are a large class of RNAs which do not encode proteins but possess regulatory functions at the level of translation in cells of various species.  There are an increasing amount of data suggesting that there are likely many more ncRNAs that exist, yet to be discovered.  Custom small RNA discovery microarrays have been shown to be an effective approach for uncovering novel ncRNAs experimentally¹ and/or to validate predicted candidate ncRNAs². (read more… )

LC Sciences and DNAVision form Strategic Marketing Alliance

Houston, TX – May 6, 2008 – LC Sciences announced today that it has entered into a strategic marketing alliance with DNAVision to increase accessibility to its custom microRNA profiling service and enhance both its customer and technical service to researchers in Europe.  LC Sciences’ microRNA profiling service is powered by µParaflo® microfluidic technology and makes use of flexible custom microarrays for expression profiling as well as discovery of novel small RNAs and validation of predicted microRNAs.  DNAVision, specialized in molecular biology, provides a wide range of genetic services and products to the pharmaceutical, food, and biotechnology industries. (read more… )

Microfluidic technology fuels the growing microRNA revolution – LC Sciences tops 30th customer publication

Houston, TX – February 27, 2008 – LC Sciences announced today the publication of the 30th peer-reviewed study by one of its customers using the company’s microarray service for analyzing microRNA expression profiles and for discovery of novel small RNAs. These studies, by leading researchers in the field, contribute to a fast growing body of knowledge defining this recently discovered class of regulatory RNAs. (read more… )

LC Sciences First miRNA Microarray Service Provider to Offer Sanger’s miRBase 10.0 Probe Content

Houston, TX – August 9, 2007 – Taking advantage of its flexible µParaflo^®Chip Technology, Houston based LC Sciences today announced immediate availability of probe content miRBase 10.0 for their microRNA (miRNA) microarray customers. This announcement comes less than a week after Sanger Institute’s update of their sequence database for known miRNAs (miRBase)¹ to version 10.0 (http://microrna.sanger.ac.uk/sequences/). As the jump in version numbers from 9.2 to 10.0 suggests, this update marks a major milestone and features significant changes: 489 new hairpin sequences and 971 novel mature miR and miR* experimentally verified products have been added. (read more… )

LC Sciences Keeps Pace with Sanger miRBase microRNA Sequence Updates

Houston, TX – May 9, 2006 – LC Sciences announced today that the probe content of its line of standard and custom microRNA microarrays used in their comprehensive expression profiling service would keep pace with the latest version (Release 8.1) of the Sanger miRBase sequence database and that microarrays containing the new sequences are already available. The Sanger Institute released their latest version of their miRBase sequence database for known microRNAs on Friday May 5, 2006. (http://microrna.sanger.ac.uk/sequences/) This is the fifth update since the beginning of last year and updates occur whenever a significant number of experimentally verified sequences are added to the database. This update is significant because of the large number of sequences added; the total number has increased from 3518 to 3963, which include 130 new Human sequences, 70 new Mouse sequences, and 3 entirely new species: Xenopus tropicalis (177), Bos taurus (33), Rhesus lymphocryptovirus (16). (read more… )