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PepCyber Database Update – V1.2

pepcyber2_01 The current release of the PepCyber: P~Pep database V1.2 (May 2010) includes 11,269 records of interactions between 387 PPBD proteins and 1,471 substrate proteins, curated from 4,852 published studies.  This release represents a 60% increase in the number proteins covered over the previous release.

PepCyber: P~Pep is the largest public database of human protein-protein interactions mediated by phosphoprotein binding domains (PPBDs).   The database is hand curated from peer-reviewed literature and is a rich information source emphasizing the reported, experimentally validated data for specific PPBD-PPEP interactions, not a simple deposit of computational entries.  PepCyber: P~Pep is freely accessible at

  1. Gong W, Zhou D, Ren Y, Wang Y, Zuo Z, Shen Y, Xiao F, Zhu Q, Hong A, Zhou X, Gao X, Li T. (2008) PepCyber:P~PEP: a database of human protein protein interactions mediated by phosphoprotein-binding domains. Nucleic Acids Res 36(Database issue), D679-83. [article]