LC Sciences News

Visit LC Sciences at Booth #209  - May 9-10, 2012 - Frederick, MD - NCI-Frederick and Ft. Detrick Spring Research Festival

Researchers at Zhejiang University, China have not only identified 64 cucumber miRNAs, which belongs to 29 known and two novel miRNA families, but also discovered that some of the miRNAs are differentially expressed in a tissue-dependent manner1. For the first time, we detected 21 sliced targets, which reveal interaction between miRNA and target in cucumber by using the recently developed degradome sequencing approach. This report will offer a foundation for future studies of the miRNA-mediated regulatory networks in cucumber.

Yao Y, Smith LP, Petherbridge L, Watson M, Nair V. (2012) Novel microRNAs encoded by duck enteritis virus. J Gen Virology [Epub ahead of print]. [abstract] Hancock MH, Tirabassi RS, Nelson JA. (2012) Rhesus cytomegalovirus encodes seventeen microRNAs that are differentially expressed in vitro and in vivo. Virology 425(2), 133-42. [abstract] Ma M, Huang Y, Gong Z, Zhuang L, Li C, et al. (2011) Discovery of DNA Viruses in Wild-Caught Mosquitoes Using Small RNA High throughput Sequencing. PLoS

Researchers at the University of Houston used LC Sciences’ miRNA microarray service and discovered that prostacyclin (PGI2), a key vascular protector, is involved in regulating cellular microRNA (miRNA) expression through its receptors in a mouse adipose tissue-derived primary culture cell line expressing a novel hybrid enzyme gene. Their array data suggest that PGI2 regulates miRNA expression that inhibits insulin-mediated lipid deposition in cells. This is relevant because peripheral