microRNA

Biomarker

There is clinical potential for miRNA as therapeutics in neuroscience

miRNAs are important regulators of stem cell pluripotence and cellular differentiation.

They are emerging as novel strategies for well-controlled efficient differentiation of hESCs into functional lineages essential to the use of hESC biology for cell-based therapies.

Tumor differentiation state is highly predictive of neuroblastoma (NB) patient survival, and the involvement of miRNAs with NB differentiation and tumorigenic state is being explored for the development of novel therapeutic strategies.

Researchers have shown that overexpression of miRNAs, predicted to target inflammatory molecules, diminished expression of pro-inflammatory cytokines and reduced in neuroinflammation demonstrating that miRNAs can be used as a therapeutic tool to prevent the BBB dysfunction in neuroinflammation.

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LC Sciences offers a range of services applicable to clinical neuroscience research.
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RNA Sequencing Services

microRNA Profiling Services

microRNAs are small noncoding RNA molecules that function broadly as negative regulators of gene expression to control a wide range of cellular processes. A genome-wide microRNA (miRNA) expression profiling service…