Mar

11

New microRNA Publications List Available

Filed Under New Customer Publications | Leave a Comment

mirna_pubs_listHere is the latest list of publications from our customers making use of our microRNA Discovery and Profiling Services.  The current list includes more than 140 publications by some of the leading researchers in the microRNA field.  Enjoy!

Nov

2

Recent Customer Publications – microRNA Microarray Service

Filed Under New Customer Publications | Leave a Comment

Cell Development and Biology

1. Li Y, Piatigorsky J. 2009) Targeted deletion of Dicer disrupts lens morphogenesis, corneal epithelium stratification, and whole eye development. Dev Dyn 38(9), 2388-400. [abstract]

2. Lin Q, Gao Z, Alarcon RM, Ye J, Yun Z. (2009) A role of miR-27 in the regulation of adipogenesis. FEBS J 276(8):2348-58. [abstract]

3. Lin Y, Liu X, Cheng Y, Yang J, Huo Y, Zhang C. (2009) Involvement of MicroRNAs in hydrogen peroxide-mediated gene regulation and cellular injury response in vascular smooth muscle cells. J Biol Chem 284(12), 7903-913. [abstract]

Neuroscience

4. Siegel G, Obernosterer G, Fiore R, Oehmen M, Bicker S, Christensen M, Khudayberdiev S, Leuschner PF, Busch CJ, Kane C, Hübel K, Dekker F, Hedberg C, Rengarajan B, Drepper C, Waldmann H, Kauppinen S, Greenberg ME, Draguhn A, Rehmsmeier M, Martinez J, Schratt GM. (2009) A functional screen implicates microRNA-138-dependent regulation of the depalmitoylation enzyme APT1 in dendritic spine morphogenesis. Nat Cell Biol 11(6), 705-16. [abstract]

5. Hill JM, Zhao Y, Clement C, Neumann DM, Lukiw WJ. (2009) HSV-1 infection of human brain cells induces miRNA-146a and Alzheimer-type inflammatory signaling. Neuroreport 20(16), 1500-505. [abstract]

6. Wang X, Liu P, Zhu H, Xu Y, Ma C, Dai X, Huang L, Liu Y, Zhang L, Qin C. (2009) miR-34a, a microRNA up-regulated in a double transgenic mouse model of Alzheimer’s disease, inhibits bcl2 translation. Brain Res Bull [Epub ahead of print] [abstract]  Read more

Oct

1

Customers Publishing Raw Images of µParaflo® Microfluidic Chip Data

Filed Under New Customer Publications | Leave a Comment

LC Sciences’ customers have been publishing raw images of its µParaflo® microfluidic chip data since the company began offering the microRNA microarray service back in 2005.  So we thought we would give you a quick look at some of these images.  (For a more thorough look check out the individual screenshots here)The exceedingly high quality of the data coming from these chips makes the results so clear that it makes sense to illustrate by showing the actual scanned image of the array itself.  “We are continually amazed that our customers choose to publish images of the array in the main text of the articles as a means present research results.  This is not something you typically see with data from a standard microarray and reflects the strength of our advanced technology”.  Chris Hebel, LC Sciences LLC.  Read more

Sep

17

Featured Publication

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Yale researchers put LC Sciences’ microRNA Microarray Service to work to study microRNA involvement in obesity.  Their results strongly suggest that miR-27 represents a new class of adipogenic inhibitors and may play a role in the pathological development of obesity.  [abstract]

Sep

11

Enabling microRNA Discoveries – LC Sciences tops 100th customer publication

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Houston, TX – September 4, 2009 – LC Sciences announced today the publication of the 100th peer-reviewed study by one of its customers using the company’s microarray service for analyzing microRNA (miRNA) expression profiles and for discovery of novel small RNAs. These studies, by leading researchers in the field, contribute to a fast growing body of knowledge defining this recently discovered class of regulatory RNAs.

To date, miRNAs have proven to be extremely important part of the gene expression regulation mechanism. Expression profiling and functional studies conducted so far indicate that miRNAs participate in the regulation of almost every cellular process investigated and this is evident in the amount of relevant findings being translating into published reports.

MicroRNA Publications

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