Dec

15

Supplier Comparison – microRNA Microarray Content

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mirbase_supplier_comparisonLC Sciences’ microRNA microarrays cover all species for which sequence data are available in the miRBase Sequence Database and the Plant MicroRNA Database.  Other suppliers are not covering miRs from the Plant MicroRNA database and their arrays covering the miRBase are somewhat out of date.  Since miRBase is being continually updated, a flexible microarray platform is necessary to keep current with the latest miRBase version (14.0 released in September of 2009).

Supplier miRBase             Version           Coverage Total        miRBase     Entries miRBase           Release Date
LC Sciences 14.0 10883 Sept 2009
Agilent 12.0 8619 Sept 2008
Affymetrix 11.0 6396 April 2008
Exiqon 11.0 6396 April 2008
Invitrogen 9.0 4361 Oct 2006

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Oct

15

Press Release – LC Sciences First miRNA Microarray Service Provider to Offer Plant MicroRNA Database (PMRD) Probe Content

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Houston, TX – October 15, 2009 – Taking full advantage of its flexible µParaflo® Biochip Technology, Houston based LC Sciences today announced immediate availability of probe content from the newly created Plant MicroRNA Database (PMRD) for their microRNA (miRNA) microarray customers. This announcement comes immediately following a publication in Nucleic Acids Research introducing the public database1. The PMRD integrates available plant miRNA data deposited in other public databases, gleaned from the recent literature, and data generated by the database organizers. It is freely available at http://bioinformatics.cau.edu.cn/PMRD. Read more

Oct

8

Plant MicroRNA Database Arrays Now Available

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LC Sciences now has standard arrays available for all species listed in the newly created Plant MicroRNA Database (PMRD). 

The plant miRNA database (PMRD) integrates available plant miRNA data deposited in public databases, gleaned from the recent literature, and data generated by the database organizers. This database contains sequence information, secondary structure, target genes, expression profiles and a genome browser.

In total, there are 8433 miRNAs collected from 121 plant species in PMRD, including model plants and major crops such as Arabidopsis, rice, wheat, soybean, maize, sorghum, barley, etc. For Arabidopsis, rice, poplar, soybean, cotton, medicago and maize, the possible target genes for each miRNA with a predicted interaction site are included in the database.  

In addition, miRNA expression profiles are provided in the PMRD, including some data generated with previous versions of  LC Sciences’ Plants microRNA Microarray.

The PMRD is freely available at http://bioinformatics.cau.edu.cn/PMRD.

  1. Zhang Z, Yu J, Li D, Zhang Z, Liu F, Zhou X, Wang T, Ling Y, Su Z.  (2009) PMRD: plant microRNA database.  Nucleic Acids Res  [Epub ahead of print]