LC Sciences Blog » microrna profiling http://www.lcsciences.com/blog Technologies for Genomics and Proteomics Discoveries Tue, 31 Aug 2010 23:10:52 +0000 http://wordpress.org/?v=2.9.2 en hourly 1 microRNA Discovery & Profiling http://www.lcsciences.com/blog/product-information/microrna-discovery-profiling http://www.lcsciences.com/blog/product-information/microrna-discovery-profiling#comments Wed, 21 Jul 2010 22:33:37 +0000 admin http://www.lcsciences.com/blog/?p=297 microRNA Discovery & Profiling is a post from: LC Sciences Blog. More information about LC Sciences can be here.

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microRNA Discovery & Profiling is a post from: LC Sciences Blog. More information about LC Sciences can be here.

]]> http://www.lcsciences.com/blog/product-information/microrna-discovery-profiling/feed 0 Seq-Array: microRNA Discovery and Profiling Using a Customizable Workflow http://www.lcsciences.com/blog/information/seq-array-microrna-discovery-and-profiling-using-a-customizable-workflow http://www.lcsciences.com/blog/information/seq-array-microrna-discovery-and-profiling-using-a-customizable-workflow#comments Wed, 26 May 2010 14:27:12 +0000 admin http://www.lcsciences.com/blog/?p=214 Seq-Array: microRNA Discovery and Profiling Using a Customizable Workflow is a post from: LC Sciences Blog. More information about LC Sciences can be here.

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Seq-ArraySM provides an efficient pathway from an initial broad search to focused biological insights.

Seq-ArraySM offers a customized solution to high-throughput genome-wide microRNA discovery and profiling, especially in species with limited or no microRNA sequence information available. This unique combination of the latest deep sequencing technology, advanced bioinformatics, and our innovative µParaflo® custom microarray platform leverages all these technologies to form a comprehensive service package tailored to your specific research needs.

Seq-Array: microRNA Discovery and Profiling Using a Customizable Workflow is a post from: LC Sciences Blog. More information about LC Sciences can be here.

]]> http://www.lcsciences.com/blog/information/seq-array-microrna-discovery-and-profiling-using-a-customizable-workflow/feed 0 Seminar – MicroRNA Discovery & Profiling http://www.lcsciences.com/blog/events/seminar-microrna-discovery-profiling http://www.lcsciences.com/blog/events/seminar-microrna-discovery-profiling#comments Wed, 20 Jan 2010 15:07:29 +0000 admin http://www.lcsciences.com/blog/?p=169 Seminar – MicroRNA Discovery & Profiling is a post from: LC Sciences Blog. More information about LC Sciences can be here.

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Presented by – Dr. Christoph Eicken & Dr. Qi Zhu, LC Sciences
12:00 pm Conference Room 2

as part of – Texas Medical Center BioResearch Product Faire

Houston, TX (Marriott Medical Center) – January 16, 2010

Seminar – MicroRNA Discovery & Profiling is a post from: LC Sciences Blog. More information about LC Sciences can be here.

]]> http://www.lcsciences.com/blog/events/seminar-microrna-discovery-profiling/feed 0 Plant & Animal Genomes Conference http://www.lcsciences.com/blog/events/plant-animal-genomes-conference http://www.lcsciences.com/blog/events/plant-animal-genomes-conference#comments Fri, 08 Jan 2010 14:34:35 +0000 admin http://www.lcsciences.com/blog/?p=160 Plant & Animal Genomes Conference is a post from: LC Sciences Blog. More information about LC Sciences can be here.

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Plant & Animal Genomes XVIII Conference
Jan 9 – 13, 2010 – San Diego, CA     Visit LC Sciences at Booth #509

The Premier and Largest Ag-Genomics Meeting in the World

5 Reasons to Select LC Sciences for your microRNA Profiling Studies in Agriculturally Important Species

  • 100% miRBase Coverage – Version 14.0 – 10883 microRNAs – 115 species
  • 100% Plant Database Coverage – Version 1.0 of the Plant microRNA Database – 8433 microRNAs covering 121 plant species
  • Experience – More than 6000 samples processed since 2005 – Over 130 customer publications
  • Custom Microarrays – Expression profiling of any species
  • Deep Sequencing – Discovery or novel small RNAs in any species

Plant & Animal Genomes Conference is a post from: LC Sciences Blog. More information about LC Sciences can be here.

]]> http://www.lcsciences.com/blog/events/plant-animal-genomes-conference/feed 0 MicroRNAs in Dendritic Spine Morphogenesis http://www.lcsciences.com/blog/new-customer-publications/130 http://www.lcsciences.com/blog/new-customer-publications/130#comments Mon, 09 Nov 2009 16:15:31 +0000 admin http://www.lcsciences.com/blog/?p=130 MicroRNAs in Dendritic Spine Morphogenesis is a post from: LC Sciences Blog. More information about LC Sciences can be here.

]]> Researchers at Heidelberg University used a combination of expression profiling of miRNAs and subsequent functional inhibitory screening in primary hippocampal neurons to identify miRNAs in the synaptodendritic compartment that function during synaptic development.  MicroRNA microarrays identified ten mature miRNAs that were enriched and four mature miRNAs that were strongly depleted in synaptosomes compared with whole forebrain. Northern blot analysis on selected miRNAs confirmed the microarray results.  Subsequent functional screening identified miR-138 as a negative regulator of dendritic spine size and revealed that mRNA encoding acyl-protein thioesterase 1 (APT1) is a miR-138 target in neurons.

Siegel G, Obernosterer G, Fiore R, Oehmen M, Bicker S, Christensen M, Khudayberdiev S, Leuschner PF, Busch CJ, Kane C, Hübel K, Dekker F, Hedberg C, Rengarajan B, Drepper C, Waldmann H, Kauppinen S, Greenberg ME, Draguhn A, Rehmsmeier M, Martinez J, Schratt GM.  (2009) A functional screen implicates microRNA-138-dependent regulation of the depalmitoylation enzyme APT1 in dendritic spine morphogenesis.  Nat Cell Biol 11(6), 705-16.  [abstract]

MicroRNAs in Dendritic Spine Morphogenesis is a post from: LC Sciences Blog. More information about LC Sciences can be here.

]]> http://www.lcsciences.com/blog/new-customer-publications/130/feed 0 Featured Publication – MicroRNA Profiling and Head and Neck Cancer http://www.lcsciences.com/blog/new-customer-publications/featured-publication-microrna-profiling-and-head-and-neck-cancer http://www.lcsciences.com/blog/new-customer-publications/featured-publication-microrna-profiling-and-head-and-neck-cancer#comments Fri, 25 Sep 2009 15:27:23 +0000 admin http://www.lcsciences.com/blog/?p=70 Featured Publication – MicroRNA Profiling and Head and Neck Cancer is a post from: LC Sciences Blog. More information about LC Sciences can be here.

]]> head_and_neck_cancerRecent advances in microRNA expression profiling have led to a better understanding of the HNOC pathogenesis. This will lead to the identification of specific microRNA expression patterns that may become powerful biomarkers for diagnosis and prognosis of HNOC. In addition, these microRNAs may also serve as therapeutic targets for novel strategies of HNOC prevention and therapeutics. (read more)

Featured Publication – MicroRNA Profiling and Head and Neck Cancer is a post from: LC Sciences Blog. More information about LC Sciences can be here.

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