LC Sciences Blog

microRNA Discovery & Profiling

microRNA Discovery & Profiling is a post from: LC Sciences Blog. More information about LC Sciences can be here.

PepCyber Database Update – V1.2

The current release of the PepCyber: P~Pep database V1.2 (May 2010) includes 11,269 records of interactions between 387 PPBD proteins and 1,471 substrate proteins, curated from 4,852 published studies. This release represents a 60% increase in the number proteins covered over the previous release. PepCyber: P~Pep is the largest public database of human protein-protein interactions mediated [...]

PepCyber Database Update – V1.2 is a post from: LC Sciences Blog. More information about LC Sciences can be here.

Small RNA Sequencing – Sample Data

InDepth Data Analysis Report Includes: Map to Reference Sequence Includes custom construction of reference database(s) for mapping – miRBase, genome, etc Sequence data can be aligned to any publicly available small RNA databases for annotation of known small RNA Unknown small RNAs can be aligned with reference genomes Additional Bioinformatics Analysis Classification of all mapped reads Length distribution of mapped sequences Annotation documentation [...]

Small RNA Sequencing – Sample Data is a post from: LC Sciences Blog. More information about LC Sciences can be here.

Featured Article – MicroRNAome of Porcine Pre- and Postnatal Development

The domestic pig is of enormous agricultural significance and valuable models for many human diseases. Information concerning the pig microRNAome (miRNAome) has been long overdue and elucidation of this information will permit an atlas of microRNA (miRNA) regulation functions and networks to be constructed. Here we performed a comprehensive search for porcine miRNAs on ten [...]

Featured Article – MicroRNAome of Porcine Pre- and Postnatal Development is a post from: LC Sciences Blog. More information about LC Sciences can be here.

New Sample Submission Form – microRNA Microarray Service

Please nte that the sample submission form for microRNA Microarray Service has been updated due to the update of miRBase to version 15. If you have a previous version of the form saved locally, please replace with this new form. Click the link below or visit www.lcsciences.com to download the form. Thank You New Sample Submission Form [...]

New Sample Submission Form – microRNA Microarray Service is a post from: LC Sciences Blog. More information about LC Sciences can be here.

July 2010 Newsletter

July 2010 Newsletter is a post from: LC Sciences Blog. More information about LC Sciences can be here.

Featured Publication – Costimulation-Dependent Expression of MicroRNA-214 Increases the Ability of T Cells To Proliferate by Targeting Pten

T cell activation requires signaling through the TCR and costimulatory molecules, such as CD28. MicroRNAs (miRNAs) are small noncoding RNAs that regulate gene expression posttranscriptionally and are also known to be involved in lymphocyte development and function. In this paper, we set out to examine potential roles of miRNAs in T cell activation, using genome-wide [...]

Featured Publication – Costimulation-Dependent Expression of MicroRNA-214 Increases the Ability of T Cells To Proliferate by Targeting Pten is a post from: LC Sciences Blog. More information about LC Sciences can be here.

New Transcriptome Sequencing Service

Transcriptomics, or genome-wide expression profiling, aims to catalogue the complete set of RNA transcripts produced by the genome, including mRNAs, non-coding RNAs and small RNAs. Transcriptomics provides new biological insight and can be used to determine the structure of genes, their splicing patterns and other post transcriptional modifications, to detect rare and novel transcripts, and [...]

New Transcriptome Sequencing Service is a post from: LC Sciences Blog. More information about LC Sciences can be here.

New Higher Density Array

30K Custom Array Design - LC Sciences has completed development of a new microfluidic chip design containing 30K features. We are currently accepting early access orders on a case-by-case basis for custom arrays built on this design for both microRNA profiling and epitope mapping applications. All of our array designs are based on the patented µParaflo® [...]

New Higher Density Array is a post from: LC Sciences Blog. More information about LC Sciences can be here.

MicroRNA-378, a Novel Regulator of Heat Shock Transcription Factor-1, Involves Development of Cardiac Hypertrophy

Oral Presentations From the WORLD CONGRESS OF CARDIOLOGY Scientific Sessions Beijing, China 16–19 June 2010 MicroRNA-378, a Novel Regulator of Heat Shock Transcription Factor-1, Involves Development of Cardiac Hypertrophy Jie Yuan1, Hong Ma1, Hui Gong1, Ning Zhou1, Yanyan Liang1, Yuhong Niu1, Yunzeng Zou1,2 1-Shanghai Institute of Cardivascular Diseases, 2- Zhongshan Hospital and Institutes of Biomedical Sciences, Fudan University (Shanghai, China) Introduction: HSF1, [...]

MicroRNA-378, a Novel Regulator of Heat Shock Transcription Factor-1, Involves Development of Cardiac Hypertrophy is a post from: LC Sciences Blog. More information about LC Sciences can be here.