April 26th, 2010
miRBase microRNA Sequence Database Updated to Release 15
The latest version (15) of the miRBase sequence database for known miRNAs was released today.
miRBase 15 is freely available at http://www.mirbase.org/. You can find a quick summary for the new release at ftp://mirbase.org/pub/mirbase/CURRENT/README.
Highlights of the new release:
- Release 15 represents a major update to the database increasing the number of mature miRNA sequences by a full 48% over release 14.
- This latest release features a total of 15,632 mature miRNA sequences.
- The number of verified microRNAs has increased from 10,883 to 14,197 hairpin precursor miRNAs.
- 18 new species have been added bringing the total to 133 species.
- Many sequences have been updated or revised.
- New sequences have been added to important model species – Human (219), Mouse (11), Rat (1), Drosophila (218), Nematode sp. (311), Arabidopsis (9).
- New sequences have been added to important agricultural species – Cow (50), Pig (98), Silkworm (396), Peanut (23), Cotton sp.(24), Orange sp.(25), Rice (33), Sorghum (8), Corn (61).
- A total of 526 new plant sequences and 53 new virus sequences
- Other important new species include – Zebra Finch, Japanese Killifish, Yellow Fever & West Nile Mosquitos, Castor Oil Plant
This updated probe content is currently available on all of our standard or custom microRNA microarrays.
About miRBase
The miRBase database1 provides a searchable online repository for published microRNA sequences and associated annotation. miRBase also provides a gene naming and nomenclature function in the miRBase
Registry. The data are freely available to all through the web interface at http://www.mirbase.org/ and in flatfile form from ftp://mirbase.org/pub/mirbase/.
More information about LC Sciences is available at http://www.lcsciences.com.
- Griffiths-Jones S, Grocock R, van Dongen S, Bateman A, Enright A. miRBase: microRNA sequences, targets and gene nomenclature. Nucleic Acids Res 34(Database issue), D140–D144. [abstract]
